HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 22632939, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | Benzyloxyamine hydrochloride | HCID 102312 | — |
| Reactant | HCID 22632977 | HCID 22632977 | — |
| Product | HCID 22632939 | HCID 22632939 | 98.3% |
Reaction Steps
Using General Method 2, the reaction of carbonyldiimidazole (2.76 g, 16.8 mmol), 2-(2-fluoro-anilino)-4,5-difluorobenzoic acid (Example R, 4.08 g, 15.3 mmol), O-benzylhydroxylamine hydrochloride (2.44 g, 15.3 mmol), and triethylamine (2.3 mL, 16.8 mmol) provided 5.6 g of the crude title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06331538B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-51a233bcb37b434c90fcc1a827171c85 |
| Source note | uspto-grants-2001_12 |