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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2270276Generated: October 30, 2026

HCID 22632929, compound → HCID 9887217, compound

https://huagongshe.com/reaction/2270276

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22632929HCID 22632929—
CatalystPalladiumHCID 23938—
ProductHCID 9887217HCID 988721792.8%

Reaction Steps

Using the General Method 6A, the reaction of 10% Pd/C (0.057 g) with 1-(4-methoxyphenyl)-6-fluoro-3-benzyloxy-7-(4-methylpiperazin-1-yl)-1H-quinazoline-2,4-dione (Example P-1, 0.17 g, 0.35 mmol) afforded 0.13 g of the title compound as a solid, mp 195-196° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06331538B1
Source datasetuspto-grants-2001_12
ORD IDord-0168e9bdbd5b4bf78e9102a8a7d5d0c3
Source noteuspto-grants-2001_12