Phenylsilane → HCID 22633023, compound

Participants

Reaction Steps

Phenylsilane (0.07 mL, 0.56 mmol) and palladium tetrakistriphenylphosphine (17 mg, 0.015 mmol) were added to a solution of 3-allyloxy-1-benzyl-6-fluoro-7-pyrrolidin-1-yl-1H-quinazoline-2,4-dione (Example B-4, 0.15 g, 0.4 mmol) in 10 mL of dichloromethane at 0° C. The mixture was stirred for 17 hours and filtered to give 0.06 g of the title compound as a solid, mp 234-236° C.

Provenance & Evidence