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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2270300Generated: November 1, 2026

HCID 22632935, compound → HCID 22633029, compound

https://huagongshe.com/reaction/2270300

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22632935HCID 22632935—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
ProductHCID 22633029HCID 2263302993.5%

Reaction Steps

Using the method of Example 56, 20% Pd/C (20 mg), 3-benzyloxy-6-fluoro-1-(4-methylphenyl)-7-pyrrolidin-1-yl-1H-pyrido[2,3-d]pyrimidine-2,4-dione (Example R-4, 0.16 g, 0.33 mmol) were combined in 25 mL of THF, to give 0.11 g of the title compound as a solid, mp 228-230° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06331538B1
Source datasetuspto-grants-2001_12
ORD IDord-1ec1f0e073c04010baa3391faaaaaacc
Source noteuspto-grants-2001_12