HCID 12052032, compound → HCID 12052033, compound

HRID 2270309Notes

Reaction equation

HRID 2270309 reaction equation
C([O:3][C:4](=[O:21])[C:5]([S:12][C:13]1[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][CH:14]=1)([CH3:11])[CH2:6][CH:7]=[C:8]([CH3:10])[CH3:9])C>CO.[OH-].[Na+]>[CH3:20][O:19][C:16]1[CH:15]=[CH:14][C:13]([S:12][C:5]([CH3:11])([CH2:6][CH:7]=[C:8]([CH3:10])[CH3:9])[C:4]([OH:21])=[O:3])=[CH:18][CH:17]=1

Participants

4

Reactant 1

HCID 12052032HCID 12052032, compound

Product 1

HCID 12052033HCID 12052033, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 14798Sodium HydroxideSolvent

Procedure

2-(4Methoxy-phenylsulfanyl)-2,5-dimethyl-hex-4-enoic acid was prepared starting from 2-(4-methoxy-phenylsulfanyl)-2,5-dimethyl-hex-4-enoic acid ethyl ester (2.0 g, 6.4 mmol) dissolved in methanol (50 ml) and 10 N NaOH (20 ml). The resulting reaction mixture was worked up as outlined in Example 1. Yield is 1.9 g, 99% of low melting solid. MS: 280 (M+H)+.

Workup

  1. customThe resulting reaction mixture

Sources & evidence

ORD record
ord-fd3ca96d4d9a47aeb312c5f3a7f5ba33
Source dataset
uspto-grants-2001_12
Patent number
US06331563B1

Reaction notes

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