HCID 11056131, compound → HCID 53756990, compound

HRID 2270322Notes

Reaction equation

HRID 2270322 reaction equation
[CH2:1]([O:3][C:4](=[O:21])[CH:5]([S:10]([C:13]1[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][CH:14]=1)(=[O:12])=[O:11])[CH2:6][CH2:7][CH2:8][CH3:9])[CH3:2].Cl[CH2:23][C:24]1[CH:37]=[CH:36][C:27]([O:28][CH2:29][CH2:30][N:31]([CH2:34][CH3:35])[CH2:32][CH3:33])=[CH:26][CH:25]=1>>[CH2:1]([O:3][C:4](=[O:21])[C:5]([CH2:23][C:24]1[CH:25]=[CH:26][C:27]([O:28][CH2:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35])=[CH:36][CH:37]=1)([S:10]([C:13]1[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][CH:14]=1)(=[O:11])=[O:12])[CH2:6][CH2:7][CH2:8][CH3:9])[CH3:2]

Participants

3

Reactant 2

HCID 11056131HCID 11056131, compoundHCID 124936912-[4-(Chloromethyl)phenoxy]-N,N-diethylethan-1-amine

Product 1

HCID 53756990HCID 53756990, compound

Procedure

2-[4-(2-Diethylamino-ethoxy)-benzyl]-2-(4-methoxy-benzenesulfonyl)-hexanoic acid ethyl ester was prepared according to the general method as outlined in example 12. Starting from 2-(4-methoxy-benzenesulfonyl)-hexanoic acid ethyl ester (4 g, 12.7 mmol) and [2-(4-chloromethyl-phenoxy)-ethyl]-diethylamine (3.38 g, 14 mmol). Yield 8.21 g crude (100%); brown oil; MS: 520.4 (M+H)+.

Sources & evidence

ORD record
ord-60fdcd4206cf459898147987a62a55f0
Source dataset
uspto-grants-2001_12
Patent number
US06331563B1

Reaction notes

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