Ethyl 2-bromooctanoate → HCID 54290310, compound

HRID 2270328Notes

Reaction equation

HRID 2270328 reaction equation
Br[CH:2]([CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])[C:3]([O:5][CH2:6][CH3:7])=[O:4].[CH3:14][N:15]1[CH:19]=[CH:18][N:17]=[C:16]1[SH:20]>>[CH2:6]([O:5][C:3](=[O:4])[CH:2]([S:20][C:16]1[N:15]([CH3:14])[CH:19]=[CH:18][N:17]=1)[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])[CH3:7]

Participants

3

Reactant 2

HCID 95580Ethyl 2-bromooctanoateHCID 178480602HCID 178480602, compound

Product 1

HCID 54290310HCID 54290310, compound

Procedure

2-(1-methyl-1H-imidazol-2-ylsulfanyl)octanoic acid ethyl ester was prepared according to the general method as outlined in example 9. Starting from ethyl 2-bromooctanoate (12.1 g, 48 mmol) and 1-methyl-2-mercapto imidazole (5 g, 43.8 mmol). Yield: 12 g (96%); clear oil; MS: 285 (M+H)+.

Sources & evidence

ORD record
ord-e274d8bbab574c66a16c610a3b3cacba
Source dataset
uspto-grants-2001_12
Patent number
US06331563B1

Reaction notes

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