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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2270334Generated: October 31, 2026

Sodium Hydroxide → 2-(Octane-1-sulfonyl)3-[4-(2-piperidin-yl-ethoxy)phenyl]-propionic acid

https://huagongshe.com/reaction/2270334

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant2-(Octane-1-sulfonyl) 3-[4-(2-piperidin-yl-ethoxy)phenyl]-propionic acid ethyl esterHCID 10961872—
SolventEthanolHCID 702—
Product2-(Octane-1-sulfonyl)3-[4-(2-piperidin-yl-ethoxy)phenyl]-propionic acidHCID 21267975—

Reaction Steps

2-(Octane-1-sulfonyl)-3-[4-(2-piperidin-yl-ethoxy)-phenyl]-propionic acid was prepared is according to the general method as outlined in example 9. Starting from 2-(octane-1-sulfonyl)-3-[4(2-piperidin-yl-ethoxy)-phenyl]-propionic acid ethyl ester (8.9 g, 18 mmol), ethanol (25 mL) and 10 N sodium hydroxide (25 mL). Yield 6.0g (72%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06331563B1
Source datasetuspto-grants-2001_12
ORD IDord-8fb18c22902741dcab6626bc42809b75
Source noteuspto-grants-2001_12