1-(6-Bromo-pyridin-2-ylmethyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid methoxy-methyl-amide → HCID 57754718, compound

Participants

Reaction Steps

Experimental conditions analogous to those described for Step 6 of Example 60 from 90 mg (0.22 mmol) of 1-(6-bromo-pyridin-2-ylmethyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid methoxy-methyl-amide in 1 mL THF and 0.25 mL 2M 4-tert-butylphenylmagnesium bromide. Yield: 80 mg of a white solid. LC-MSD, m/z for C26H23BrN2O2 [M+H]+=475.0, 477.0; HPLC retention time: 2.9 min.

Provenance & Evidence