HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1,1'-Biphenyl)-4-sulfonic acid → (1,1'-Biphenyl)-4-sulphonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1,1'-Biphenyl)-4-sulfonic acid | HCID 16673 | — |
| Reactant | Phosphorus pentachloride | HCID 24819 | — |
| Solvent | Water | HCID 962 | — |
| Product | (1,1'-Biphenyl)-4-sulphonyl chloride | HCID 74192 | — |
Reaction Steps
4-Biphenyl sulfonic acid (2.4 g, 10 mmol) was heated to 100 C with phosphorus pentachloride (2.1 g, 10 mmol) overnight. The reaction was cooled to RT, diluted with water, filtered and washed with water. The solid was then triturated with EtOAc-ether and the beige solid was used in the next reaction without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06331542B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-60356324443b4a2a85976d4615598b2e |
| Source note | uspto-grants-2001_12 |