Dimethyl Sulfoxide → HCID 18331423, compound

Participants

Reaction Steps

To a mixture of 3-chloromethyl-4-ethylnitrobenzene (4.0 g) and dimethyl sulfoxide (50 ml), sodium cyanide (982 mg) was added. The reaction mixture was stirred at room temperature for 3 h and then ethyl acetate, n-hexane and water were added. The organic layer was washed with a saturated aqueous sodium chloride solution, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the titled compound quantitatively.

Provenance & Evidence