Dimethyl Sulfoxide → HCID 18331406, compound

Participants

Reaction Steps

To a mixture of the compound (3.0 g) obtained in Example 25a, α,α′-dichloro-o-xylene (4.15 g) and dimethyl sulfoxide (200 ml), potassium t-butoxide (3.55 g) was added and after stirring the resulting mixture at room temperature for 3 h, ethyl acetate and water were added. The organic layer was washed with a saturated aqueous sodium chloride solution, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the titled compound (1.36 g) (yield, 29%).

Provenance & Evidence