HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(Benzenesulfonyl)thiophene-2-sulfonyl chloride → HCID 22998399, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(Benzenesulfonyl)thiophene-2-sulfonyl chloride | HCID 580877 | — |
| Reactant | 4-Bromo-3-methylisoxazol-5-amine | HCID 10487519 | — |
| Product | HCID 22998399 | HCID 22998399 | 59% |
Reaction Steps
N-(4-Bromo-3-methyl-5-isoxazolyl)-5-(benzenesulfonyl)thiophene-2-sulfonamide was prepared in the same manner as described in Example 2 from 5-amino-4-bromo-3-methylisoxazole and 5-benzenesulfonylthiophene-2-sulfonyl chloride in 59% yield. Purification was achieved by recrystallization from ethyl acetate/hexanes to give a crystalline solid, m.p. 139-142° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06331637B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-1244f61eeaa442be9215b5a40c84b919 |
| Source note | uspto-grants-2001_12 |