HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 2-[3,4-(Methylenedioxy)benzyl]benzo[b]thiophene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Triethylsilane | HCID 12052 | — |
| Reactant | a-(2-Benzo[b]thienyl)-3,4-(methylenedioxy)benzyl alcohol | HCID 49964046 | — |
| Product | 2-[3,4-(Methylenedioxy)benzyl]benzo[b]thiophene | HCID 22998407 | — |
Reaction Steps
2-[3,4-(methylenedioxy)benzyl]benzo[b]thiophene was prepared by the method of Example 47B using a-(2-benzo[b]thienyl)-3,4-(methylenedioxy)benzyl alcohol (6.2 mmoles, 1.8 g), triethylsilane (6.8 mmoles, 1.1 ml) CH2Cl2 (50 ml) and TFA (12.4 mmoles, 0.95 ml). Recrystallization from hexanes provided 1.2 g (73%) of a light orange solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06331637B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-5ae45cd65b7942f8a074dcb40a5158f7 |
| Source note | uspto-grants-2001_12 |