HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 2-Phenylfuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Phenyl dihydrogen orthoborate | HCID 78412 | — |
| Reactant | Furan, 2-bromo- | HCID 2776190 | — |
| Catalyst | Tetrakis(triphenylphosphine)palladium | HCID 11979704 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | 2-Phenylfuran | HCID 519363 | — |
Reaction Steps
2-phenylfuran was prepared by the method of Example 32C from 2-bromofuran (0.93 g, 6.3 mmol), sodium carbonate (18 ml of 2 M aqueous solution), phenyl boric acid (0.93 g, 7.6 mmol) and tetrakis (triphenylphosphine) palladium (O) (0.36 g, 0.32 mmol). Flash chromatography with hexane provided 0.79 g (87% yield) of a colorless liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06331637B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-efdb5d411c934b5086187503713ce59b |
| Source note | uspto-grants-2001_12 |