HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromothiophene → 2-(3-methylphenyl)thiophene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromothiophene | HCID 13851 | — |
| Reactant | 3-Tolylboronic acid | HCID 2733950 | — |
| Product | 2-(3-methylphenyl)thiophene | HCID 3564188 | — |
Reaction Steps
2-(3-tolyl)thiophene was prepared in the same manner as described in Example 116A using 2-bromothiophene and 3-methylphenylboronic acid. The crude product was purified by flash chromatography on silica gel using hexane as the eluent (86% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06331637B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-d81d56416942491fb092d197218ee0a6 |
| Source note | uspto-grants-2001_12 |