1-(Chloromethoxy)-2-methoxyethane → HCID 69983700, compound

HRID 2270717Notes

Reaction equation

HRID 2270717 reaction equation
[CH3:1][C:2]1[C:6]([CH3:7])=[C:5]([NH:8][S:9]([C:12]2[S:13][CH:14]=[CH:15][CH:16]=2)(=[O:11])=[O:10])[O:4][N:3]=1.[CH3:17][O:18][CH2:19][CH2:20][O:21][CH2:22]Cl>>[CH3:17][O:18][CH2:19][CH2:20][O:21][CH2:22][N:8]([C:5]1[O:4][N:3]=[C:2]([CH3:1])[C:6]=1[CH3:7])[S:9]([C:12]1[S:13][CH:14]=[CH:15][CH:16]=1)(=[O:10])=[O:11]

Participants

3

Reactant 2

HCID 775901-(Chloromethoxy)-2-methoxyethaneHCID 22998429HCID 22998429, compound

Product 1

HCID 69983700HCID 69983700, compoundYield 34%

Procedure

N-(methyoxyethoxymethyl)-N-(3,4-dimethyl-5-isoxazolyl)thiophene-2-sulfonamide was prepared in the same manner as described in Example 32B using N-(3,4-dimethyl-5-isoxazolyl)thiophene-2-sulfonamide and methoxyethoxymethyl chloride resulting in 34% yield. HPLC analysis of the crude oil obtained after workup showed that the oil was approximately 96% pure and so was used in the next step without further purification.

Workup

  1. customHPLC analysis of the crude oil obtained after workup
  2. customso was used in the next step without further purification

Sources & evidence

ORD record
ord-c7e92098c989492ca93e736a20ce94ac
Source dataset
uspto-grants-2001_12
Patent number
US06331637B1

Reaction notes

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