HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminophenylboronic acid → N-(3-methyl-5-isoxazolyl)-5-(3-aminophenyl)thiophene-2-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminophenylboronic acid | HCID 92269 | — |
| Reactant | N-(3-methyl-5-isoxazolyl)-5-bromothiophene-2-sulfonamide | HCID 22998516 | — |
| Product | N-(3-methyl-5-isoxazolyl)-5-(3-aminophenyl)thiophene-2-sulfonamide | HCID 22998520 | — |
Reaction Steps
N-(3-methyl-5-isoxazolyl)-5-(3-aminophenyl)thiophene-2-sulfonamide was prepared in the same manner as described in Example 32C from 3-amino benzene boronic acid (256 mg, 1.87 mmol) and N-(3-methyl-5-isoxazolyl)-5-bromothiophene-2-sulfonamide (55 mg, 1.7 mmol). At Purification by column chromatography using 15% MeOH/CHCl3 gave 318 mg (56%) of the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06331637B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-cd265cb573ee41b392b3a7be03a2589a |
| Source note | uspto-grants-2001_12 |