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(5-Methylthiophen-2-yl)boronic acid → N-[5-(5-methyl-2-thienyl)thiophene-2-sulfonyl]pyrrole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (5-Methylthiophen-2-yl)boronic acid | HCID 2734374 | — |
| 反応物 | N-(5-bromothiophenesulfonyl)pyrrole | HCID 23445587 | — |
| 生成物 | N-[5-(5-methyl-2-thienyl)thiophene-2-sulfonyl]pyrrole | HCID 22998476 | 72% |
反応手順
N-[5-(5-methyl-2-thienyl)thiophene-2-sulfonyl]pyrrole was prepared in the same manner as described in Example 32C from 2-methylthiophene-5-boronic acid and N-(5-bromothiophene-2-sulfonyl) pyrrole. Purification by column chromatography using 2% ether/hexanes gave the pure sulfonamide in 72% yield as a white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06331637B1 |
| 出典データセット | uspto-grants-2001_12 |
| ORD ID | ord-b28905de5e0746b3928326fe6ffcf578 |
| 出典メモ | uspto-grants-2001_12 |