HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-3-methylisoxazol-5-amine → N-(4-Bromo-3-methyl-5-isoxazolyl)-2-[(4-methylphenoxy)methyl]thiophene-3-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-3-methylisoxazol-5-amine | HCID 10487519 | — |
| Reactant | 2-[(4-Methylphenoxy)methyl]thiophene-3-sulfonyl chloride | HCID 23445257 | — |
| Product | N-(4-Bromo-3-methyl-5-isoxazolyl)-2-[(4-methylphenoxy)methyl]thiophene-3-sulfonamide | HCID 23445507 | 64% |
Reaction Steps
N-(4-bromo-3-methyl-5-isoxazolyl)-2-[(4-methylphenoxy)methyl]-thiophene-3-sulfonamide was prepared, as described in Example 2, by reacting 3-chlorosulfonyl-2-[(4-methylphenoxy)methyl]thiophene with 5-amino-4-bromo-3-methylisoxazole, resulting in a 64% yield, m.p. 128-130° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06331637B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-aaa6a59c45a5463e8c8b4f7b9ad7c35a |
| Source note | uspto-grants-2001_12 |