HCID 20714638, compound → HCID 68819479, compound

HRID 2270762Notes

Reaction equation

HRID 2270762 reaction equation
[Cl:1][C:2]1[CH:26]=[C:25]([C:27]([NH:29][CH2:30][C:31]2[CH:36]=[CH:35][CH:34]=[C:33]([OH:37])[CH:32]=2)=[O:28])[CH:24]=[CH:23][C:3]=1[C:4]([NH:6][C@H:7]([C:20]([OH:22])=[O:21])[CH2:8][NH:9][C:10]([C:12]1[CH:16]=[C:15]([N+]([O-])=O)N[N:13]=1)=[O:11])=[O:5].Cl[C:39]1C=C(C(NCC2C=CC=C(O)C=2)=O)C=CC=1C(N[C@H](C(O)=O)CNC(C1C=CC=CN=1)=O)=O.ClC1C=C(C(NCC2C=CC=C(O)C=2)=O)C=CC=1C(N[C@H](C(O)=O)CNC(C1C=CC=C(C)N=1)=O)=O.ClC1C=C(C(NCC2C=CC=C(O)C=2)=O)C=CC=1C(N[C@H](C(O)=O)CNC(C1C=CC(CCC(Br)CBr)=CN=1)=O)=O.ClC1C=C(C(NCC2C=CC=C(O)C=2)=O)C=CC=1C(N[C@H](C(O)=O)CNC(C1C=NC=CC=1)=O)=O.ClC1C=C(C(NCC2C=CC=C(O)C=2)=O)C=CC=1C(N[C@H](C(O)=O)CNC(C1C(Cl)=NC=CC=1)=O)=O.ClC1C=C(C(NCC2C=CC=C(O)C=2)=O)C=CC=1C(N[C@H](C(O)=O)CNC(C1C=NC(Cl)=CC=1)=O)=O.ClC1C=C(C(NCC2C=CC=C(O)C=2)=O)C=CC=1C(N[C@H](C(O)=O)CNC(C1C(OC)=NC(OC)=CC=1)=O)=O.ClC1C=C(C(NCC2C=CC=C(O)C=2)=O)C=CC=1C(N[C@H](C(O)=O)CNC(C1C(O)=NC=CC=1)=O)=O.ClC1C=C(C(NCC2C=CC=C(O)C=2)=O)C=CC=1C(N[C@H](C(O)=O)CNC(C1C=NC=CN=1)=O)=O.ClC1C=C(C(NCC2C=CC=C(O)C=2)=O)C=CC=1C(N[C@H](C(O)=O)CNC(C1C(C(NC2C=CC(Cl)=CN=2)=O)=NC=CN=1)=O)=O.ClC1C=C(C(NCC2C=CC=C(O)C=2)=O)C=CC=1C(N[C@H](C(O)=O)CNC(C1C(O)=NC(O)=NC=1)=O)=O.ClC1C=C(C(NCC2C=CC=C(O)C=2)=O)C=CC=1C(N[C@H](C(O)=O)CNC(C1N=C(O)N=C(O)C=1)=O)=O>>[Cl:1][C:2]1[CH:26]=[C:25]([C:27]([NH:29][CH2:30][C:31]2[CH:36]=[CH:35][CH:34]=[C:33]([OH:37])[CH:32]=2)=[O:28])[CH:24]=[CH:23][C:3]=1[C:4]([NH:6][C@H:7]([C:20]([OH:22])=[O:21])[CH2:8][NH:9][C:10]([C:12]1[NH:13][CH:39]=[CH:15][CH:16]=1)=[O:11])=[O:5]

Participants

14

Reactant 13

HCID 20714638HCID 20714638, compoundHCID 20714639HCID 20714639, compoundHCID 20714648HCID 20714648, compoundHCID 20714649HCID 20714649, compoundHCID 20714655HCID 20714655, compoundHCID 20714656HCID 20714656, compoundHCID 20714657HCID 20714657, compoundHCID 68819460HCID 68819460, compoundHCID 68823731HCID 68823731, compoundHCID 135714528HCID 135714528, compoundHCID 178522967HCID 178522967, compoundHCID 178522968HCID 178522968, compoundHCID 178522969HCID 178522969, compound

Product 1

HCID 68819479HCID 68819479, compound

Procedure

N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(5-nitropyrazole-3-carbonyl)]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(pyridine-2-carbonyl)]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(6-methylpyridine-2-carbonyl)]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[5-(3,4-dibromobutyl)pyridine-2-carbonyl]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(pyridine-3-carbonyl)]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(2-chloropyridine-3-carbonyl)]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(6-chloropyridine-3-carbonyl)]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(2,6-dimethoxypyridine-3-carbonyl)]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(2-hydroxypyridine-3-carbonyl)]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(pyrazine-2-carbonyl)]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[3-[[(5-chloro-2-pyridinyl)amino]carbonyl]pyrazine-2-carbonyl]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(2,4-dihydroxypyrimidine-5-carbonyl)]amino-L-alanine; N-[2-chloro-4-[[[(3-hydroxyphenyl)methyl]amino]carbonyl]benzoyl]-3-[(2,4-dihydroxypyrimidine-6-carbonyl)]amino-L-alanine),

Sources & evidence

ORD record
ord-94fb1bcb0e814029b5cd52812d4ec818
Source dataset
uspto-grants-2001_12
Patent number
US06331640B1

Reaction notes

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