反应详情

温度

25 °C

Aminoguanidine bicarbonate (1.75 moles) was dissolved in 9.3-10.0 M sulphuric acid solution. A solution of 2,3-dichlorobenzoyl cyanide (1 mole) in acetonitrile was added and the suspension stirred at 20-30° C. for 42-48 hours. The crude product was filtered and washed with water. The solid was added to sodium hydroxide solution below 35° C., then the product was filtered, washed with water and dried at 80-90° C. to obtain 1.5 as a yellow solid in 66% yield.

1. filtrationThe crude product was filtered
2. washwashed with water
3. additionThe solid was added to sodium hydroxide solution below 35° C.
4. filtrationthe product was filtered
5. washwashed with water
6. customdried at 80-90° C.