HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → 1-(6-Bromo-pyridin-2-ylmethyl)-3-(6-dimethylamino-pyridine-3-carbonyl)-1H-quinolin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | HCID 57754507 | HCID 57754507 | — |
| Product | 1-(6-Bromo-pyridin-2-ylmethyl)-3-(6-dimethylamino-pyridine-3-carbonyl)-1H-quinolin-4-one | HCID 57754601 | — |
Reaction Steps
Experimental conditions analogous to those described for Example 141, from 42 mg (0.092 mmol) of 1-(6-bromo-pyridin-2-ylmethyl)-3-(6-chloro-pyridine-3-carbonyl)-1H-quinolin-4-one and 1 mL 2 M dimethylamine solution. Yield: 17 mg of a yellow powder. LC-MSD, m/z for C23H19BrN4O2 [M+H]+=463.0, 465.0; HPLC retention time: 0.6 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07557213B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-4a105281731e44efad52bbfcff688ec3 |
| Source note | uspto-grants-2009_07 |