HCID 10566532, compound → HCID 22731781, compound

HRID 2270973Notes

Reaction equation

HRID 2270973 reaction equation
[C:1]1([S:7]([N:10]2[C:18]3[C:13](=[CH:14][C:15]([Cl:19])=[CH:16][CH:17]=3)[CH:12]=[C:11]2[CH3:20])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:21][C:22](OC(C)=O)=[O:23].[Al+3].[Cl-].[Cl-].[Cl-]>>[C:22]([C:12]1[C:13]2[C:18](=[CH:17][CH:16]=[C:15]([Cl:19])[CH:14]=2)[N:10]([S:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)(=[O:9])=[O:8])[C:11]=1[CH3:20])(=[O:23])[CH3:21]

Participants

3

Reactant 2

HCID 10566532HCID 10566532, compoundHCID 86584360HCID 86584360, compound

Product 1

HCID 22731781HCID 22731781, compoundYield 86%

Procedure

1-Benzenesulfonyl-5-chloro-2-methylindole prepared in accordance with the literature (J. Org. Chem., 47, 757 (1982) was reacted with Ac2O/AlCl3 in a similar manner described in Reference example 2 (3) to give 3-acetyl-1-benzenesulfonyl-5-chloro-2-methylindole. Yield: 86%.

Sources & evidence

ORD record
ord-2393cf388d1a4d059b0868cf55870dbc
Source dataset
uspto-grants-2001_12
Patent number
US06333323B1

Reaction notes

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