Cyclohexene ethanol → 2-Phenylbenzothiazol-5-ol

Participants

Reaction Steps

Palladium hydroxide (100 mg) was added to a solution of 27 (260 mg, 0.8 mmol) of ethanol/cyclohexene (5 mL/2 mL) followed by warming for reflux for 16 h. The reaction mixture was cooled and the catalyst was removed by filtration (through Celite). The solvent was evaporated to provide compound 29 as a white solid. Synthesis of 5-(oxiran-2-ylmethoxy)-2-phenylbenzothiazole (59):

Provenance & Evidence