HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Benzylpiperidine → 3-Benzyl-1-[4-(5-methoxyindol-3-yl)butanoyl]piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Benzylpiperidine | HCID 114551 | — |
| Reactant | 2-Chloro-1-methylpyridinium iodide | HCID 167069 | — |
| Reactant | 5-Methoxyindole-3-butyric acid | HCID 11241777 | — |
| Product | 3-Benzyl-1-[4-(5-methoxyindol-3-yl)butanoyl]piperidine | HCID 15858890 | — |
Reaction Steps
Equimolar amounts of 3-benzylpiperidine and 4-(5-methoxyindol-3-yl)butanoic acid (preparation analogous to Example 1a) are reacted at room temperature with addition of 2-chloro-1-methyl-pyridinium iodide. After customary work-up, 3-benzyl-1-[4-(5-methoxyindol-3-yl)butanoyl]piperidine is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06333339B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-72e4c4d8705f47999e64218b11513e05 |
| Source note | uspto-grants-2001_12 |