Carbon Dioxide → HCID 18329802, compound

Participants

Reaction Conditions

Reaction Steps

2-Pyridylacetonitrile (10 ml, 94.0 mmol) was added dropwise over 20 minutes to an ice-cooled solution of sodium ethoxide (34 ml, 2.76M, 94.0 mmol) in ethanol (50 ml), and the mixture stirred at 0° C. for 30 minutes. Ethyldiazoacetate (9.9 ml, 94.0 mmol) was added dropwise over 15 minutes and the reaction allowed to warm to room temperature and stirred for a furter 18 hours. Water (300 ml) was added, the mixture neutralised with solid carbon dioxide, and the resulting precipitate filtered and dried to afford the title compound, (13.0 g, 60%) as a brown solid.

Provenance & Evidence