HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-chloroacetoacetate → HCID 86585189, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-chloroacetoacetate | HCID 69484 | — |
| Reactant | HCID 289466 | HCID 289466 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 86585189 | HCID 86585189 | 38.5% |
Reaction Steps
A mixture of 3,4,5-trimethoxyphenylurea (400 mg) and ethyl-4-chloroacetoacetate (350 mg) in dioxane (0.8 ml) is heated at reflux for 4 hours. After one hour at 25° C. the precipitate is recovered by filtration and recrystallized from methanol (3 ml), to give 210 mg of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06333346B1 |
| Source dataset | uspto-grants-2001_12 |
| ORD ID | ord-c27a576339d14f0583a32cf5168799b7 |
| Source note | uspto-grants-2001_12 |