Benzoxazole → 5-(Oxiran-2-ylmethoxy)-2-phenylbenzothiazole
Reaction equation
[C:1]1([C:7]2[S:8][C:9]3[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][C:10]=3[N:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[O:17]1[C:21]2[CH:22]=[CH:23]C=CC=2N=C1>>[O:17]1[CH2:21][CH:22]1[CH2:23][O:16][C:13]1[CH:14]=[CH:15][C:9]2[S:8][C:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)=[N:11][C:10]=2[CH:12]=1Participants
3
Procedure
Compound 59 was prepared in the manner of compound 6 substituting compound 29 for compound 8 in partC-5 of Example 1.
Sources & evidence
- ORD record
- ord-41a1402fd9464d14bd8af58575f8fc29
- Source dataset
- uspto-grants-2005_02
- Patent number
- US06849632B2
Reaction notes
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