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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2271176Generated: November 1, 2026

p-Tolylacetic acid → N-[(4-methylphenyl)acetyl]alanine iso-butyl ester

https://huagongshe.com/reaction/2271176

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(4-methylphenyl)acetyl]alanine iso-butyl esterHCID 53936136—

Reaction Steps

Following General Procedure I above, and using 4-methylphenylacetic acid (Aldrich) and L-alanine iso-butyl ester (prepared following General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06333351B1
Source datasetuspto-grants-2001_12
ORD IDord-9f545e88d9694149811d14195f62bd85
Source noteuspto-grants-2001_12