Water → Benzoin acetate

HRID 2271230Notes

Reaction equation

HRID 2271230 reaction equation
[C:1]1([C:7]([CH:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[OH:10])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:17](OC(=O)C)(=[O:19])[CH3:18].O>S(=O)(=O)(O)O.ClCCl>[C:17]([O:8][CH:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)[C:9](=[O:10])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)(=[O:19])[CH3:18]

Participants

6

Reactant 3

HCID 962WaterHCID 7918Acetic AnhydrideHCID 8400Benzoin

Product 1

HCID 95416Benzoin acetate

Reagents, catalysts & solvents 2

HCID 1118Sulfuric AcidCatalystHCID 6344DichloromethaneSolvent

Conditions

Temperature
25 °C

Procedure

2 g of benzoin with 15 ml of acetic anhydride and a few drops of sulphuric acid are added to a reactor with stirring and at room temperature (25° C.) for 15 hours. Water and dichloromethane are added to the reaction mixture. The organic phase is recovered after separating by settling, dried over sodium sulphate, filtered and then concentrated to dryness under vacuum.

Workup

  1. customThe organic phase is recovered
  2. customafter separating
  3. dry with materialdried over sodium sulphate
  4. filtrationfiltered
  5. concentrationconcentrated to dryness under vacuum

Sources & evidence

ORD record
ord-27f7f951a9e74a7c9a5fc6c6b4a6a1ea
Source dataset
uspto-grants-2001_12
Patent number
US06333414B1

Reaction notes

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