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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2271370Generated: October 25, 2026

Potassium Carbonate → 1118915-78-8

https://huagongshe.com/reaction/2271370

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant(Chloro(phenylmethoxy)phosphoryl)oxymethylbenzeneHCID 4641201—
Reactantbenzyl 3-(2-(benzyloxy)-4-(ethoxymethoxy)-5-isopropylphenyl)-4-(1-methyl-1H-indol-5-yl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-1-carboxylateHCID 67339760—
SolventAcetoneHCID 180—
Product1118915-78-8HCID 135565962—

Reaction Steps

Dibenzyl phosphorochloridate was added to the solution of benzyl 3-(2-(benzyloxy)-4-(ethoxymethoxy)-5-isopropylphenyl)-4-(1-methyl-1H-indol-5-yl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-1-carboxylate and potassium carbonate in acetone. The reaction mixture was stirred at room temperature overnight. After removal of solvent, the reaction mixture was purified by column chromatography to produce pale yellow oil, which was hydrogenated to give the desired.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09120745B2
Source datasetuspto-grants-2015_09
ORD IDord-7b243eb4d4644f7db3ffcc6beceb1654
Source noteuspto-grants-2015_09