HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1118915-78-8
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | (Chloro(phenylmethoxy)phosphoryl)oxymethylbenzene | HCID 4641201 | — |
| Reactant | benzyl 3-(2-(benzyloxy)-4-(ethoxymethoxy)-5-isopropylphenyl)-4-(1-methyl-1H-indol-5-yl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-1-carboxylate | HCID 67339760 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1118915-78-8 | HCID 135565962 | — |
Reaction Steps
Dibenzyl phosphorochloridate was added to the solution of benzyl 3-(2-(benzyloxy)-4-(ethoxymethoxy)-5-isopropylphenyl)-4-(1-methyl-1H-indol-5-yl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-1-carboxylate and potassium carbonate in acetone. The reaction mixture was stirred at room temperature overnight. After removal of solvent, the reaction mixture was purified by column chromatography to produce pale yellow oil, which was hydrogenated to give the desired.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120745B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-7b243eb4d4644f7db3ffcc6beceb1654 |
| Source note | uspto-grants-2015_09 |