HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromobenzyl bromide → 1-(3-Bromo-benzyl)-3-(2,3-dihydro-benzo[1,4]dioxine-6-carbonyl)-1H-quinolin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromobenzyl bromide | HCID 69979 | — |
| Reactant | 3-(2,3-Dihydro-benzo[1,4]dioxine-6-carbonyl)-1H-quinolin-4-one | HCID 57754543 | — |
| Product | 1-(3-Bromo-benzyl)-3-(2,3-dihydro-benzo[1,4]dioxine-6-carbonyl)-1H-quinolin-4-one | HCID 57754661 | 23% |
Reaction Steps
Experimental conditions analogous to those described for Step 3 of Example 1, from 3-(2,3-Dihydro-benzo[1,4]dioxine-6-carbonyl)-1H-quinolin-4-one (70 mg, 0.228 mmol) and 74 mg (0.296 mmol) of 1-Bromo-3-bromomethyl-benzene, to give 25 mg of desired compound. LCMS (M+H)+: 476.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07557213B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-515f84265c1548388c3d3cce7aa311b1 |
| Source note | uspto-grants-2009_07 |