HuagongsheHuagongshe Chemistry Print Report · For research reference only
m,alpha-Dichlorotoluene → 1-(3-Chloro-benzyl)-3-(2,3-dihydro-benzo[1,4]dioxine-6-carbonyl)-1H-quinolin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m,alpha-Dichlorotoluene | HCID 12103 | — |
| Reactant | 3-(2,3-Dihydro-benzo[1,4]dioxine-6-carbonyl)-1H-quinolin-4-one | HCID 57754543 | — |
| Product | 1-(3-Chloro-benzyl)-3-(2,3-dihydro-benzo[1,4]dioxine-6-carbonyl)-1H-quinolin-4-one | HCID 57754534 | 24.4% |
Reaction Steps
Experimental conditions analogous to those described for Step 3 of Example 1, from 3-(2,3-Dihydro-benzo[1,4]dioxine-6-carbonyl)-1H-quinolin-4-one 70 mg (0.228 mmol) and 71.1 mg (0.296 mmol) 1-Chloro-3-chloromethyl-benzene, to give 24 mg of desired compound. LCMS (M+H)+: 432.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07557213B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-79795f5e90bc4702b8153e640d843ab0 |
| Source note | uspto-grants-2009_07 |