HRID2271545

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CN(C(=O)OC(C)(C)C)C1CCN(c2ccc(N)cn2)C1

HCID57652013

未命名化合物

HCID66715483

1-(6-Bromo-4-chloroquinolin-3-yl)ethan-1-one

C11H7BrClNO

PRODUCTS

生成物

结构：CC(=O)c1cnc2ccc(Br)cc2c1Nc1ccc(N2CCC(N(C)C(=O)OC(C)(C)C)C2)nc1

HCID68092208

未命名化合物

收率 51%

PROCEDURE

实验过程

Following general procedure C, 1-(6-bromo-4-chloroquinolin-3-yl)ethanone (285 mg, 1.0 mmol) was reacted with tert-butyl (1-(5-aminopyridin-2-yl)pyrrolidin-3-yl)(methyl)carbamate (440 mg, 1.50 mmol) to afford the desired product (273 mg, 51%) as an orange solid. ESI MS m/z 540 [C26H30BrN5O3+H]+