HuagongsheHuagongshe Chemistry Print Report · For research reference only
(6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone → HCID 178519792, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone | HCID 66715111 | — |
| Reactant | HCID 178478720 | HCID 178478720 | — |
| Product | HCID 178519792 | HCID 178519792 | 52% |
Reaction Steps
Following general procedure C, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (466 mg, 1.5 mmol) was reacted with trans-4-(pyrrolidin-1-ylmethyl)cyclohexanamine dihydrochloride (847 mg, 3.0 mmol) to afford the desired product (180 mg, 52%) as an off-white solid. ESI MS m/z 456 [C24H30BrN3O+H]+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-644bb9bbed59418d93e5eb8c64a3d4f0 |
| Source note | uspto-grants-2015_09 |