反应详情

Following general procedure B, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (211 mg, 0.680 mmol) was reacted with N,N-dimethyl-1-(piperidin-4-yl)methanamine (97 mg, 0.680 mmol) to afford the desired product (160 mg, 46%) as a yellow glass: ESI MS m/z 417 [C21H26BrN3O+H]+.