反应详情

Following general procedure B, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (210 mg, 0.680 mmol) was reacted with 4-(pyrrolidin-1-ylmethyl)piperidine (229 mg, 1.36 mmol) to afford the desired product (210 mg, 70%) as a yellow semisolid: ESI MS m/z 443 [C23H28BrN3O+H]+.