HuagongsheHuagongshe Chemistry Print Report · For research reference only
(6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone → HCID 178519796, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone | HCID 66715111 | — |
| Reactant | HCID 178479265 | HCID 178479265 | — |
| Product | HCID 178519796 | HCID 178519796 | 24% |
Reaction Steps
Following general procedure C, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (220 mg, 0.708 mmol) was reacted with trans-4-(pyrrolidin-1-yl)cyclohexanamine hydrochloride (350 mg, 2.08 mmol) to afford the desired product (75 mg, 24%) as an off-white solid: ESI MS m/z 442 [C23H28BrN3O+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-55a6b55476184d4392f678f3f0db32ee |
| Source note | uspto-grants-2015_09 |