HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(6-Bromo-4-chloroquinolin-3-yl)-2-methylpropan-1-one → HCID 178450270, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(6-Bromo-4-chloroquinolin-3-yl)-2-methylpropan-1-one | HCID 68091993 | — |
| Reactant | HCID 178419079 | HCID 178419079 | — |
| Product | HCID 178450270 | HCID 178450270 | 81.6% |
Reaction Steps
Following general procedure B, 1-(6-bromo-4-chloroquinolin-3-yl)-2-methylpropan-1-one (10 g, 32.0 mmol) was reacted with tert-butyl trans-4-aminocyclohexylcarbamate (10.3 g, 48.0 mmol) to afford the desired product (12.8 g, 81%) as an off-white solid: ESI MS m/z 491 [C24H32BrN3O3+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-952cd055ee9a4d5793b401ee513f5be1 |
| Source note | uspto-grants-2015_09 |