HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Diethyl-1,4-cyclohexanediamine → N1-[6-Bromo-3-(methylsulfonyl)quinolin-4-yl]-N4,N4-diethylcyclohexane-1,4-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Diethyl-1,4-cyclohexanediamine | HCID 349884 | — |
| Reactant | 6-Bromo-4-chloro-3-(methylsulfonyl)quinoline | HCID 66715245 | — |
| Product | N1-[6-Bromo-3-(methylsulfonyl)quinolin-4-yl]-N4,N4-diethylcyclohexane-1,4-diamine | HCID 68092001 | 87% |
Reaction Steps
Following general procedure B, 6-bromo-4-chloro-3-(methylsulfonyl)quinoline (161 mg, 0.500 mmol) was reacted with N1,N1-diethylcyclohexane-1,4-diamine (170 mg, 1.00 mmol) to afford the desired product (197 mg, 87%) as a white solid: ESI MS m/z 454 [C20H28BrN3O2S+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-a72b8abb1f074b2bafe6193c9fd60684 |
| Source note | uspto-grants-2015_09 |