HuagongsheHuagongshe Chemistry Print Report · For research reference only
(6-Bromo-4-chloro-7-fluoroquinolin-3-yl)(cyclopropyl)methanone → HCID 178484099, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (6-Bromo-4-chloro-7-fluoroquinolin-3-yl)(cyclopropyl)methanone | HCID 66715407 | — |
| Reactant | HCID 178484105 | HCID 178484105 | — |
| Product | HCID 178484099 | HCID 178484099 | 54.2% |
Reaction Steps
Following general procedure C, (6-bromo-4-chloro-7-fluoroquinolin-3-yl)(cyclopropyl)methanone (297 mg, 0.900 mmol) was reacted with trans-N1,N1-dimethylcyclohexane-1,4-diamine (290 mg, 1.35 mmol) to afford the desired product (212 mg, 54%) as an off-white solid: ESI MS m/z 435 [C21H25BrFN3O+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-b5c80407cf1b4286a6108f5bed3c6bf5 |
| Source note | uspto-grants-2015_09 |