1,1-Dimethylethyl 4-(5-amino-2-pyrimidinyl)-1-piperazinecarboxylate → HCID 66715920, compound

Participants

Reaction Steps

Following general procedure B, 1-(6-bromo-4-chloroquinolin-3-yl)ethanone (300 mg, 1.06 mmol) was reacted with tert-butyl 4-(5-aminopyrimidin-2-yl)piperazine-1-carboxylate (495 mg, 1.59 mmol) to afford the desired product (250 mg, 44%) as a yellow solid: ESI MS m/z 527, [C24H27BrN6O3+H]+

Provenance & Evidence