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HRID2271604

反应详情

EQUATION

反应方程式

HRID 2271604 的结构方程式

REACTANTS

反应物

2
结构：CC(=O)c1cnc2ccc(Br)cc2c1Cl
HCID66715483

1-(6-Bromo-4-chloroquinolin-3-yl)ethan-1-one

C11H7BrClNO

结构：CC(C)(C)OC(=O)NC1CCCN(c2ccc(N)cn2)C1
HCID66715840

Carbamic acid, N-[1-(5-amino-2-pyridinyl)-3-piperidinyl]-, 1,1-dimethylethyl ester

C15H24N4O2

PRODUCTS

生成物

1
结构：CC(=O)c1cnc2ccc(Br)cc2c1Nc1ccc(N2CCCC(NC(=O)OC(C)(C)C)C2)nc1
HCID66716437

未命名化合物

收率 55.7%

PROCEDURE

实验过程

Following general procedure B, 1-(6-bromo-4-chloroquinolin-3-yl)ethanone (194 mg, 0.681 mmol) was reacted with tert-butyl 1-(5-aminopyridin-2-yl)piperidin-3-ylcarbamate (210 mg, 0.821 mmol) to afford the desired product (205 mg, 55%) as a brown solid: ESI MS m/z 540, [C26H30BrN5O3+H]+