HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol → HCID 66715526, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol | HCID 66715127 | — |
| Reactant | HCID 86692875 | HCID 86692875 | — |
| Product | HCID 66715526 | HCID 66715526 | 102.7% |
Reaction Steps
Following general procedure D, tert-butyl 4-(5-(3-acetyl-6-bromoquinolin-4-ylamino)pyridin-2-yl)piperazine-1-carboxylate (55 mg, 0.104 mmol) was reacted with 2,6-dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol (36 mg, 0.125 mmol) to afford the desired product (65 mg, 72%) as an green oil: ESI MS m/z 608, [C31H31Cl2N5O4+H]+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-3ac20333844440b486f12c028ecd6487 |
| Source note | uspto-grants-2015_09 |