HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-nitropyrimidine → HCID 66716414, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-nitropyrimidine | HCID 82544 | — |
| Reactant | 4-(N-Boc-amino)piperidine | HCID 723833 | — |
| Product | HCID 66716414 | HCID 66716414 | 87.1% |
Reaction Steps
Following General procedure H, 2-chloro-5-nitropyrimidine (500 mg, 3.1 mmol) was reacted with tert-butyl piperidin-4-ylcarbamate (683 mg, 3.5 mmol) followed by reduction to afford the desired product (792 mg, 87%) as a purple solid: ESI MS m/z 294 [C14H23N5O2+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-4389edc296a249f8bb989bd40353ea38 |
| Source note | uspto-grants-2015_09 |