HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-nitropyridine → HCID 66715567, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-nitropyridine | HCID 78308 | — |
| Reactant | 1-Boc-3-aminopyrrolidine | HCID 2756370 | — |
| Product | HCID 66715567 | HCID 66715567 | 47.2% |
Reaction Steps
Following General procedure H, 2-chloro-5-nitropyridine (500 mg, 3.1 mmol) was reacted with tert-butyl 3-aminopyrrolidine-1-carboxylate (632 mg, 3.5 mmol) followed by reduction to afford the desired product (407 mg, 47%) as a purple solid: ESI MS m/z 279 [C14H22N4O2+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-105e065825654de28d50b2679477eb2f |
| Source note | uspto-grants-2015_09 |