HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanolamine → 2-[(5-Aminopyridin-2-yl)amino]ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanolamine | HCID 700 | — |
| Reactant | 2-Chloro-5-nitropyridine | HCID 78308 | — |
| Product | 2-[(5-Aminopyridin-2-yl)amino]ethanol | HCID 3015333 | 65% |
Reaction Steps
Following General procedure H, 2-chloro-5-nitropyridine (500 mg, 3.1 mmol) was reacted with 2-aminoethanol (213 mg, 3.5 mmol) followed by reduction to afford the desired product (306 mg, 65%) as a purple solid: ESI MS m/z 154 [C7H11N3O+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-9c83006317f1461c9b6a91cd5cdb4bc7 |
| Source note | uspto-grants-2015_09 |