HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethylethylenediamine → N2-(2-(dimethylamino)ethyl)pyridine-2,5-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethylethylenediamine | HCID 66053 | — |
| Reactant | 2-Chloro-5-nitropyridine | HCID 78308 | — |
| Product | N2-(2-(dimethylamino)ethyl)pyridine-2,5-diamine | HCID 16772731 | 50.1% |
Reaction Steps
Following General procedure H, 2-chloro-5-nitropyridine (500 mg, 3.1 mmol) was reacted with N1,N1-dimethylethane-1,2-diamine (308 mg, 3.5 mmol) followed by reduction to afford the desired product (280 mg, 50%) as a purple solid: ESI MS m/z 181 [C9H16N4+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-56266039bb564a3392b4d0cef9b2bd16 |
| Source note | uspto-grants-2015_09 |