HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 1-(5-aminopyridin-2-yl)piperidin-4-ylcarbamate → HCID 86692879, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 1-(5-aminopyridin-2-yl)piperidin-4-ylcarbamate | HCID 22557725 | — |
| Reactant | (6-Bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone | HCID 66715111 | — |
| Product | HCID 86692879 | HCID 86692879 | 75% |
Reaction Steps
Following General procedure C, (6-bromo-4-chloroquinolin-3-yl)(cyclopropyl)methanone (311 mg, 1 mmol) was reacted with tert-butyl 1-(5-aminopyridin-2-yl)piperidin-4-ylcarbamate (439 mg, 1.5 mmol) to afford the desired product (423 mg, 75%) as a yellow solid: ESI MS m/z 566 [C28H32BrN5O3+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09120749B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-957ae760b4d846f4b9d1cf11ee204b01 |
| Source note | uspto-grants-2015_09 |